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As he often does, Joel on Software talks about programming, but what he says applies to many broader things.
People who only know one world get really smarmy, and every time they hear about the complications in the other world, it makes them think that their world doesn't have complications. But they do. You've just moved beyond them because you are proficient in them.
Think Mac vs. PC vs. Linux. Or U.S.A. vs. Europe. Or west vs. east, north vs. south. Divorces. Office politics. Laundry.