So far I have been pretty lucky with the side effects of this round of chemotherapy. I've had three treatments (of 12) since early October, and I still have my hair. (Not even any thinning yet.) I feel a bit nauseated for the three days of the treatment itself, but not long after I am merely a somewhat tired version of normal.
But there are effects. During treatments I get frequent hiccups. Outside that time I also sneeze pretty often. I have a consistently runny nose, and sometimes the discharge is a bit pink (yummy). And yes, I get tired easily.
I've also noticed that I'm more sensitive to temperature: hot showers feel hotter, and cold diet pop bites in my throat more than it used to. That may get more severe over time.
Other colorectal cancer patients I've talked to have had it much worse, even early in their treatments. Some have been relatively healthy through the whole cycle, while others started getting ill about half-way through. I'm hoping I'm in the former category.
In other words, so far so good.